Early morning flight or night bus to Izmir then drive to Pergamum where you can visit the most beatiful cities of the Hellenistic World. The city of different healing methods like therapy with music and sound of water were first used. Visit to Aesculapium, ancient medical center built in the name of Aesculapis, "God of Medicine". Lunch and proceed to Pergamum Acropolis. Visit Trojan, Athena and Dionysos Temples, Altar of Zeus, Gymnasium of Youth, Odeon, Library, Agora, Great Theatre and Roman Bath. Kizil Avlu (Red Courtyard) served as Temple of Serapis, an Egyptian God, used like church and known as one of the "Seven Churches of Revelation". Before leaving Pergamum, visit local Archeological Museum. Return to Izmir and evening flight or bus to Istanbul.